Head-to-Head Comparison

PlushCare vs Sesame

Which GLP-1 provider is right for you? See how they compare on pricing, medications, insurance, and more.

PlushCare

Online doctor visits for weight management

4/5
From $129/visit
Insurancevideo5 meds

Sesame

Affordable doctor visits, no insurance needed

3.5/5
From $59/visit
video4 meds

Side-by-Side Comparison

Feature
PlushCare
Sesame
Our Rating
4/5
3.5/5
Monthly Price
From $129/visit
From $59/visit
Consultation Fee
$129
$59
Insurance
Yes
No
Visit Type
video
video
# of Medications
5
4
Medications
Wegovy, Ozempic, Mounjaro, Zepbound, Saxenda
Wegovy, Ozempic, Mounjaro, Zepbound
States
All 50 states
Most US states

Pros & Cons

PlushCare

  • Board-certified doctors (not just NPs)
  • Accepts many major insurance plans
  • Prescribes brand-name FDA-approved medications
  • Same-day appointments often available
  • Full primary care platform
  • Per-visit fee structure (not flat monthly)
  • Less specialized in weight loss specifically
  • Medication cost not included in visit fee

Sesame

  • Very transparent pricing
  • No insurance or membership required
  • Choose your own provider from marketplace
  • Affordable consultation fees
  • Prescribes brand-name medications
  • No integrated medication delivery
  • Less structured weight loss program
  • You manage your own pharmacy relationship
  • Support between visits is limited

Our Verdict

Both connect you with real doctors for GLP-1 prescriptions without monthly memberships. PlushCare accepts insurance and has a more integrated experience. Sesame offers marketplace-style transparency where you pick your provider and see prices upfront. Choose PlushCare if you have insurance. Choose Sesame if you're paying cash and want the cheapest consultation.

Get Started with PlushCare

From $129/visit · Accepts Insurance

Get Started with Sesame

From $59/visit · Cash-pay

Medical Disclaimer

The information on this site is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. GLP-1 receptor agonists are prescription medications. Always consult with a qualified healthcare provider before starting, stopping, or changing any medication. Individual results may vary.